Coffeecoffeecoffeecoffeecoffeecoffee
So thank goodness I'd never heard of Blue Bottle Coffee before I started working here, or I'd have been in biiiiig trouble. Or 3 feet tall. This stuff is like the crack of coffee. And they only do double shots of espresso.
One of my friends who studied psychopharmacology told me that technically, caffeine takes nearly three hours to enter the blood stream from your digestive system, and any effects you feel from coffee before that time has elapsed is purely placebo, your mind saying "ahhh, coffee." I used to believe him, but now I'm not so sure. Within thirty minutes, this stuff gets my heart racing!
Now back to workworkworkworkworkworkwork. Happy Friday!
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Ericka Lutz says:
So evil. And SOOO good.
So evil. And SOOO good. Makes Peet's feel like tepid water. I'm a convert too. Do you know they can deliver it TO YOUR HOUSE? I'm resisting. I'd never sleep again.
Dennis Shay says:
Thanks for the heads-up on Blue Bottle.
We're true coffee lovers but never heard of Blue Bottle. If it is that good , we've got to try it.
You misheard your friend:
Pharmacology
Caffeine is a central nervous system and metabolic stimulant,[31] and is used both recreationally and medically to reduce physical fatigue and restore mental alertness when unusual weakness or drowsiness occurs. Caffeine stimulates the central nervous system first at the higher levels, resulting in increased alertness and wakefulness, faster and clearer flow of thought, increased focus, and better general body coordination, and later at the spinal cord level at higher doses.[32] Once inside the body, it has a complex chemistry, and acts through several mechanisms as described below.
[edit] Metabolism
Caffeine is metabolized in the liver into three primary metabolites: paraxanthine (84%), theobromine (12%), and theophylline (4%)
Caffeine is completely absorbed by the stomach and small intestine within 45 minutes of ingestion. After ingestion it is distributed throughout all tissues of the body and is eliminated by first-order kinetics.[33]
The half-life of caffeine—the time required for the body to eliminate one-half of the total amount of caffeine consumed at a given time—varies widely among individuals according to such factors as age, liver function, pregnancy, some concurrent medications, and the level of enzymes in the liver needed for caffeine metabolism. In healthy adults, caffeine's half-life is approximately 3–4 hours. In women taking oral contraceptives this is increased to 5–10 hours,[34] and in pregnant women the half-life is roughly 9–11 hours.[35] Caffeine can accumulate in individuals with severe liver disease when its half-life can increase to 96 hours.[36] In infants and young children, the half-life may be longer than in adults; half-life in a newborn baby may be as long as 30 hours. Other factors such as smoking can shorten caffeine's half-life.[37]
Caffeine is metabolized in the liver by the cytochrome P450 oxidase enzyme system (specifically, the 1A2 isozyme) into three metabolic dimethylxanthines,[38] which each have their own effects on the body:
Each of these metabolites is further metabolized and then excreted in the urine.
Belle Yang says:
Dennis
This is so much more interesting to me than pandas--and those cuddly critters never did show up in my thread.
Ivory Madison says:
"This is so much more interesting to me than pandas..."
Hi Max,
While I'm in D.C., I'm glad to hear you only leave the office to get drugs that make you work harder. Good man.
And Belle, I am sure you are referring to something I must have missed, but this is going to be my new thing I say: "This is so much more interesting to me than pandas."
Ivory Madison
Founder and CEO, redroom.com
Darlene Arden says:
Pandas? What about Tigers?
I had interviewed Joan Embry of the San Diego Zoo years ago. She asked me about something. I got the info and called her back. She was panting as she answered the phone. I asked if I had called at a bad time. She said, "No, I was just giving a bath to the Tiger." Whenever I have a bad day after that I remembered that things could be worse: I could be giving a bath to a tiger. Thanks for making me remember that. LOL
Max Sindell says:
I Stand (sit?) Corrected
Thanks for setting us straight! I must have gotten the dispersion time confused with the half life of the chemical in the body.
Either way, it's powerful stuff.
-Max Sindell, Red Room
Eric Nichols says:
When I was in college, my
When I was in college, my best friend, a feller from Brazil, got me hooked on Yerba Mate. That really cleans out the old brain follicles. There's a coffeshop here that sells the stuff..and it's as potent as ever. :)
Darlene Arden says:
Did You say COFFEE???!
As a confessed coffee-holic I'm intrigued. I wonder if it's sold on the East Coast. I've never seen it.
I go to my local coffee shop, Sudbury Coffee Works, where they roast their own beans. (www.sudburycoffeeworks.com)
Mmmmm. Caffeine.